Forensic science has significantly evolved in the last few years, with advancements in various disciplines, including forensic odontology and forensic nanotechnology. In Legal & Administrative Order, forensic odontology plays a pivotal role for personal identification whereas nanotechnology has opened new avenues for investigation and anthropological research. This current review paper uncover the potential harmony between forensic odontology and nanotechnology, highlighting their game changing potential on identification, and investigation, as well as anthropological research. Forensic odontology, the study of dental science has long been an crucial component of forensic science and its commencement. It has proven to be stable and meticulous method for identification, particularly in cases where traditional methods, such as Fingerprint identification and Genetic sequencing, are not realistic and has been indispensable in solving various criminal cases, including sexual assault, suicide attempts and disaster victim identification of human remains. On top of that anthropologists play a crucial role in using dental traces through facial overlay methods, skeletal approximation, unique cranial characteristics, sinus variations, and bone remains. On the other hand, nanotechnology, the manipulation of matter at the nanoscale, which is generally defined as the range of 1 to 100 nanometers, has revolutionized various fields, including forensic science. This paper explores the converging fields of forensic odontology and nanotechnology, examining how these developments are revolutionizing the way we approach identification, investigation, and anthropological research.